[스크랩] 배합금기에 해당하는 약물

배합금기에 해당하는 약물

* 다음 두 약물은 원칙적으로 배합금기에 해당하지만, 용량을 조절하여 조제가 가능할 수 있다.병용 조제시에는 Drug monitoring이 절대적으로 필요하다.

 

기준약물	배합금기약물
Alcohol	ㆍ정신신경계=Barbiturates, Carbamazepine, Chloral hydrate, Meprobamate, Sedatives, TCA ㆍ근골결계=Morphine & Narcotic analgesics, Muscle relaxants ㆍ순환기=Nitrates ㆍ당뇨병=Insulin ㆍ항암제=Methotrexate
Amphetamines	ㆍCocaine ㆍ정신신경계=MAOI, Propoxyphene ㆍ음식=Tyramine-rich foods
Anesthetics	ㆍ교감신경 차단제=Adrenergic, neurone blockers ㆍ항생제=Antibiotics, Neomycin, Kanamycin ㆍ고혈압 치료제=Propranolol ㆍ정신신경계=Barbiturates, Catecholamines, MAOI, Sedatives ㆍ기타=Corticosteroids, Oxytocins, Rauwolfia alkaloids
Antibiotics	ㆍ마취제(Anesthetics) ㆍ항생제 ㆍ근이완제=Neuromuscular blockers ㆍ순환기=Procainamide, Quinidine ㆍ정신신경계=Promethazine
Anticholinesterase	ㆍFluorphate ㆍ근이완제(Muscle relaxants)
Anticoagulants	ㆍ진통제=Indomethacin, Salicylates, Mefenamate, Oxyphenbutazone, Phenylbutazone ㆍ당뇨병 치료제 ㆍ항생제 ㆍCCI4 ㆍ고지혈증=Clofibrate ㆍ갑상선 치료제=Thyroid 제제
Anticonvulsants	ㆍMethylphenidate ㆍ진통제
TCAs	ㆍAlcohol ㆍ순환기계=Guanethidine, Methyldopa, Reserpine ㆍ정신신경계=Diphenylhydantoin, MAOI ㆍSalicylates
Antidiabetics(oral)	ㆍ항응고제(Anticoagulants) ㆍ정신신경계=MAOI
Antihistamins	ㆍ중추신경 억제제(CNS depressants)
Antihypertensives	마취제(Anesthetics)
Appetite depres.	MAOI
Caffeine	MAOI, Propoxyphene
Chloramphenicol	ㆍ항응고제(Anticoagulants) ㆍ당뇨병 치료제(Antidiabetics)
Clofibrate	ㆍ항응고제(Anticoagulants)=Warfarin
Cyclopropane	Epinephrine, Levarterenol
Dexrtomethorpan	MAOI
Digitalis	ㆍCalcium salt ㆍ이뇨제(Diuretics) ㆍPropranolol
Diphenylhydantoin	ㆍDisulfiram ㆍFolic acid antagonists ㆍPhenyramidol ㆍSulfonamides
Disulfiram	ㆍAlcohol ㆍMAOI
Ephedrine	ㆍErgonovine ㆍMAOI
Epinephrine	Chloroform, Cyclopropane, Dextrothyroxine, Fluroxene, Halothane, Isoproterenol, Levothyroxine, Methoxyflurane, Phenylephrine, Sympathomimetics, Thyroid preparations
Ether	Neomycin, Propranolol
Furosemide	Muscle relaxants
Guanethidine	Anesthetics, Antidepressants, MAOI
Insulin	Alcohol
Kanamycin	Anesthetics, Antibiotics, Muscle relaxants, Procainamide

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